Zebra ZD421T
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The Zebra ZD421T is a reliable and compact 4-inch thermal-transfer desktop label printer designed for businesses that need crisp, durable labels with minimal hassle. It offers fast printing speeds, excellent print quality in both 203 dpi and 300 dpi models, and supports a wide range of label types for retail, healthcare, logistics, and office environments. With user-friendly features like five LED status icons, a simple three-button interface, and easy ribbon loading, the ZD421T ensures smooth daily operation. It provides strong connectivity options including USB, USB Host, and optional Ethernet, Serial, Wi-Fi, and Bluetooth, making it flexible for many setups. With upgradeable accessories such as cutters and peelers, plus robust Print DNA software for better security and management, the ZD421T delivers dependable performance for everyday label printing needs.
Features:
- Print resolution: 203 dpi standard, 300 dpi optional
- Print width up to 4.09 in / 104 mm
- Print speed up to 6 ips ( 203 dpi ) / 4 ips ( 300 dpi )
- New 5-button user interface with intuitive status icons
- Field-upgradable media handling ( peeler, cutter ) and communications options
- Connectivity: USB, USB Host, Ethernet, Serial, Bluetooth, Wi-Fi ( optional )
- Compatible with Zebra’s Print DNA software suite for setup, security, and management
- Easy-to-use clamshell design for quick media and ribbon changes
- Compact footprint, ideal for healthcare, retail, logistics, and light manufacturing
Applications:
- 🏥 Healthcare
- 🚚 Transportation
- ⚙️ Manufacturing
- 📦 Warehouse & Logistics
- 🛒 Retail
Specifications:
| Printing Technology | Thermal Transfer and Direct Thermal |
|
Resolution |
|
| Print Speed (Maximum) |
6 in. / 152 mm per second ( 203 dpi ) 4 in. / 102 mm per second ( 300 dpi ) |
| Print Width (Maximum) |
ZD421: 4.09 in. / 104 mm for 203 dpi 4.16 in. / 106 mm for 300 dpi ZD421 Thermal Transfer Cartridge: 4.09 in. / 104 mm for 203 and 300 dpi |
| Print Length |
6 in. / 152 mm per second ( 203 dpi )
|
| Media type |
Roll-fed or fan-fold, die cut or continuous with or without black mark, tag stock, continuous receipt paper, and wristbands |
| Media Width (min to max) |
ZD421 Direct Thermal: 0.585 in. / 15 mm to 4.25 in. / 108 mm |
| Media Thickness (min to max) | 0.003 in. ( 0.08 mm ) min. 0.0075 in. ( 0.19 mm ) max. |
| Media Roll Size (max), Core Size |
Maximum outer diameter: 5.00 in. / 127 mm Core inner diameter: 0.5 in. / 12.7 mm and 1.0 in. / 25.4 mm standard, 1.5 in. / 38.1, 2.0 in. / 50.8 mm and 3.0 in. / 76.2 mm using optional adapters |
| Maximum Ribbon Length |
ZD421 Roll: 984 ft. / 300 m; 243 ft. / 74 m ZD421 Cartridge: 243 ft. / 74 m |
| Ribbon Width |
ZD421 Roll: 1.33 in. / 33.8 mm – 4.3 in. / 109.2 mm ZD421 Cartridge: 4.3 in. / 109.2 mm |
| Ribbon Core I.D. | 300 m ribbon 1 in. / 25.4 mm 74 m ribbon 0.5 in. / 12.7 mm |
| Media Sensor |
Full width, moveable reflective / black mark sensor; multi-position transmissive / gap sensor |
| Main Interface |
|
| Options & Accessories |
|
| Case |
Dual-wall frame construction |
| Control panel |
5 status icon, 3 button user interface |
| RAM (standard Memory) |
512 MB Flash; 256 MB SD RAM |
| Drivers and software | Free-of-charge ZebraDesigner software, including set-up using Zebra Setup Utilities |
| Barcode Symbologies |
Code 11 |
| Fonts and Graphics |
16 resident expandable ZPL II bitmap fonts, two resident scalable ZPL fonts, five resident expandable EPL2 fonts, native open-type font support, Unicode compliant. China units include SimSun simplified Chinese font |
| Size (W x D x H) |
ZD421 Thermal Transfer Roll: |
| Weight |
|
| Direct Thermal or Thermal Transfer |
Direct Thermal, Thermal Transfer |
|---|---|
| dpi |
203, 300 |
| Connectivity |
USB, USB & Ethernet |







